Lack of which vitamin can lead to the disease known as Pellagra?

Pellagra is a disease that is specifically associated with a deficiency of niacin, also known as vitamin B3. Niacin plays a crucial role in energy metabolism and is essential for the function of various enzymes in the body that help convert food into energy. Its deficiency can lead to a range of symptoms collectively referred to as the three D's: dermatitis, diarrhea, and dementia. Over time, untreated niacin deficiency can result in more severe health problems.

In contrast, thiamine (vitamin B1), riboflavin (vitamin B2), and vitamin C each play important roles in the body but are not directly linked to the development of Pellagra. Thiamine deficiency leads to diseases such as beriberi, riboflavin deficiency causes ariboflavinosis, and a lack of vitamin C results in scurvy. Therefore, while all these vitamins are crucial for health, only niacin is the key nutrient associated with Pellagra.